Uptown - Upper Duval Travel Guide

Key West
Key West Butterfly and Nature Conservatory featuring flowers, zoo animals and animals
Key West Butterfly and Nature Conservatory featuring flowers, zoo animals and animals
South Beach which includes a sandy beach and a coastal town as well as a large group of people
South Beach featuring swimming, a luxury hotel or resort and a sandy beach
Key West Butterfly and Nature Conservatory showing signage

Popular places to visit

Southernmost Point

Southernmost Point

4/5(39 reviews)

Snap a memorable photograph from the edge of North America at this monumental landmark.

Southernmost Point
South Beach

South Beach

4.5/5(8 reviews)

The southernmost beach in the continental United States is a convenient sandy enclave, just minutes from the center of town.

South Beach
Key West Butterfly and Nature Conservatory showing animals, food and zoo animals

Key West Butterfly and Nature Conservatory

4.5/5(10 reviews)

With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.

Key West Butterfly and Nature Conservatory

Things to do

Florida: Key West Overseas Highway Self-Driving Tour

Florida: Key West Overseas Highway App-Based Driving Audio Tour

฿529
per traveller
76% of travellers recommend
Florida: Key West Overseas Highway App-Based Driving Audio Tour
Key West’s Old Town Treasures: A Self-Guided Audio Tour

Key West’s Old Town Treasures: A Self-Guided Audio Tour

฿518
per adult
Key West’s Old Town Treasures: A Self-Guided Audio Tour
Bahama Village Walking Tour

Bahama Village Walking Tour

฿1,037
per adult
Bahama Village Walking Tour
Key West History And Culture Walking Tour

Southernmost Key West History and Culture Small-Group Walking Tour

฿1,383
per adult
Southernmost Key West History and Culture Small-Group Walking Tour
Florida Key West Self-Guided Walking Audio Tour

Florida Key West Self-Guided Walking Audio Tour Via App

฿311
per traveller
Florida Key West Self-Guided Walking Audio Tour Via App
Southernmost Point in the Continental USA!

PRIVATE Welcome to Key West Walking Tour

฿9,510
per adult
PRIVATE Welcome to Key West Walking Tour
See all activities in Key West

Top hotels in Uptown - Upper Duval

Southernmost Beach Resort
Southernmost Beach Resort
4 out of 5
1319 Duval Street, Key West, FL
The price is ฿15,913 per night from 4 Feb to 5 Feb
฿15,913
฿20,179 total
includes taxes & fees
4 Feb - 5 Feb
Stay at this 4-star beach hotel in Key West. Enjoy free Wi-Fi, 3 outdoor pools and a full-service spa. Our guests praise the pool and the bar in their reviews. ...
8.6/10 Excellent! (2,250 reviews)
"The location especially on the beachfront was very nice. Staff were professional and very affording."

Reviewed on 2 Feb 2025

Southernmost Beach Resort
The Southernmost Inn - Adults Only
The Southernmost Inn - Adults Only
3 out of 5
525 United Street, Key West, FL
The price is ฿10,086 per night from 5 Feb to 6 Feb
฿10,086
฿12,864 total
includes taxes & fees
5 Feb - 6 Feb
Stay at this 3-star hotel in Key West. Enjoy free breakfast, 2 outdoor pools and parking (surcharge). Our guests praise the breakfast and the pool in their reviews. ...
8/10 Very Good! (1,008 reviews)
Great place. Cozy with two pools and hot tub.
"It was very good except for the coffee maker broke and getting coffee in the morning was delayed. Besides that everything was great."

Reviewed on 31 Jan 2025

The Southernmost Inn - Adults Only
The Reach Key West, Curio Collection by Hilton
The Reach Key West, Curio Collection by Hilton
4 out of 5
1435 Simonton Street, Key West, FL
The price is ฿18,188 per night from 3 Mar to 4 Mar
฿18,188
฿22,586 total
includes taxes & fees
3 Mar - 4 Mar
Stay at this 4-star beach hotel in Key West. Enjoy a full-service spa, a private beach and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.2/10 Very Good! (858 reviews)
"Fantastic property. Walking distance from everything worth doing!"

Reviewed on 24 Jan 2025

The Reach Key West, Curio Collection by Hilton
Southwinds Motel
Southwinds Motel
2 out of 5
1321 Simonton Street, Key West, FL
The price is ฿8,801 per night from 4 Feb to 5 Feb
฿8,801
฿10,850 total
includes taxes & fees
4 Feb - 5 Feb
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools and a 24-hour front desk. Our guests praise the breakfast and the pool in their reviews. ...
8.6/10 Excellent! (1,064 reviews)
"Not fancy but nice"

Reviewed on 31 Jan 2025

Southwinds Motel
Douglas House
Douglas House
3 out of 5
419 Amelia St, Key West, FL
The price is ฿9,199 per night from 5 Feb to 6 Feb
฿9,199
฿10,711 total
includes taxes & fees
5 Feb - 6 Feb
Stay at this 3-star guesthouse in Key West. Enjoy free Wi-Fi, free parking and daily housekeeping. Popular attractions Southernmost Point and Duval Street are ...
9.2/10 Wonderful! (15 reviews)
Sweet little hotel
"This was a nice little hotel on a side street off of Duval. The room was small but clean and had had all amenities except a broken coffee pot. However, there was coffee available by the pool. A good value!"

Reviewed on 31 Jan 2025

Douglas House
The Mansion on the Sea - Southernmost House in the USA
The Mansion on the Sea - Southernmost House in the USA
3 out of 5
1400 Duval Street, Key West, FL
The price is ฿18,518 per night from 6 Feb to 7 Feb
฿18,518
฿21,871 total
includes taxes & fees
6 Feb - 7 Feb
Stay at this 3-star beach hotel in Key West. Enjoy free breakfast, room service and parking (surcharge). Our guests praise the helpful staff and the property ...
9.2/10 Wonderful! (1,003 reviews)
"Staff and location could not have been nicer."

Reviewed on 1 Feb 2025

The Mansion on the Sea - Southernmost House in the USA
See all 2,945 properties in Uptown - Upper Duval
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Uptown - Upper Duval

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Old Town Key West

5/5(6 area reviews)

While visiting Old Town Key West, you might make a stop by sights like Saint Mary Star of the Sea and Ernest Hemingway Home and Museum.

Old Town Key West
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Downtown Key West

While visiting Downtown Key West, you might make a stop by sights like Duval Street and Ernest Hemingway Home and Museum.

Downtown Key West
Harry S. Truman Little White House which includes a house and cycling

Bahama Village

5/5(1 area review)

Bahama Village is noteworthy for its historical sites, and you can make a stop at top attractions like Key West Lighthouse and Keeper's Quarters Museum and Ernest Hemingway Home and Museum.

Bahama Village
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Casa Marina

While visiting Casa Marina, you might make a stop by sights like Clarence S. Higgs Memorial Beach Park and Florida Keys Beaches.

Casa Marina
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Key West Historic District

4.5/5(66 area reviews)

Travellers to Key West Historic District praise its fantastic nightlife. If you've got some more time to explore, be sure to stop by Duval Street and Saint Mary Star of the Sea.

Key West Historic District
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White Street Gallery District

If you're looking for some top things to see and do in White Street Gallery District and surrounding area, you can visit Saint Mary Star of the Sea and Clarence S. Higgs Memorial Beach Park.

White Street Gallery District

Uptown - Upper Duval Travel Guide