Photo by Hazem Abdul

Search Hotels in South Main, Houston

  • Plan, book, stay with confidence

    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Filter by

Guest rating
Guest rating
Property class

Top Trending Hotels Near South Main, Houston

Comfort Suites near Texas Medical Center - NRG Stadium
Lobby

Comfort Suites near Texas Medical Center - NRG Stadium

2.5 star property
8.6 out of 10, Excellent, (742)
"Everyone was nice and happy..will definitely stay here again "
The price is ฿3,374
฿3,948 total
includes taxes & fees
26 Jan - 27 Jan
Comfort Suites near Texas Medical Center - NRG Stadium
Wyndham Houston near NRG Park/Medical Center
View from property

Wyndham Houston near NRG Park/Medical Center

3.5 star property
7.2 out of 10, Good, (1007)
"Hot water did not work in our room. Very close to the noisy interstate. "
The price is ฿3,738
฿4,374 total
includes taxes & fees
4 Jan - 5 Jan
Wyndham Houston near NRG Park/Medical Center
Candlewood Suites Houston Medical Center, an IHG Hotel
Exterior

Candlewood Suites Houston Medical Center, an IHG Hotel

2.5 star property
7.6 out of 10, Good, (725)
"Probably will not stay there again. Other properties in the area are much better. Homeless camped out right in front of the building. "
The price is ฿2,201
฿2,575 total
includes taxes & fees
15 Jan - 16 Jan
Candlewood Suites Houston Medical Center, an IHG Hotel
Wingate Houston near NRG Park/Medical Center
Room, 2 Double Beds, Non Smoking | Desk, laptop workspace, blackout curtains, iron/ironing board

Wingate Houston near NRG Park/Medical Center

3.0 star property
6.8 out of 10, (796)
"Perfect hotel to stadium was the best feature for us will definitely come back. "
The price is ฿3,052
฿3,571 total
includes taxes & fees
4 Jan - 5 Jan
Wingate Houston near NRG Park/Medical Center
Tx Home Group - Medical Center
Shared kitchen

Tx Home Group - Medical Center

3.0 star property
6.8 out of 10, (3)
"If you dont want to stay in a apartment with a stranger, then this is NOT for you. The person i shared this apartment with was cool overall but almost burnt down the plcae 3x, the sharable portable fan stayed in her room, not considerable for others who may need to use washer and dryer and dishes to cook in, and played her music very loudly! When i booked this room i saw nothing saying "sharable" or else i would have used my $590 somewhere else but once paid it was non-refundable. Be aware...
The price is ฿2,968
฿6,216 total
includes taxes & fees
6 Jan - 7 Jan
Tx Home Group - Medical Center
Quality Inn & Suites NRG Park - Medical Center
Hypo-allergenic bedding, in-room safe, individually decorated

Quality Inn & Suites NRG Park - Medical Center

2.5 star property
6.6 out of 10, (1002)
"Great! Thanks 😊"
The price is ฿2,017
฿2,360 total
includes taxes & fees
1 Feb - 2 Feb
Quality Inn & Suites NRG Park - Medical Center
La Quinta Inn & Suites by Wyndham Deer Park
Exterior

La Quinta Inn & Suites by Wyndham Deer Park

2.5 star property
8.6 out of 10, Excellent, (358)
"Ok. Will return."
The price is ฿2,894
฿3,386 total
includes taxes & fees
8 Jan - 9 Jan
La Quinta Inn & Suites by Wyndham Deer Park
La Quinta Inn & Suites by Wyndham Houston East at Sheldon Rd
Pillow-top beds, desk, iron/ironing board, free WiFi

La Quinta Inn & Suites by Wyndham Houston East at Sheldon Rd

3.5 star property
9.2 out of 10, Wonderful, (871)
"Love that it is a gated property."
The price is ฿2,334
฿2,684 total
includes taxes & fees
19 Jan - 20 Jan
La Quinta Inn & Suites by Wyndham Houston East at Sheldon Rd
Sonesta Simply Suites Houston – NASA Clear Lake
Fridge, microwave, stovetop, dishwasher

Sonesta Simply Suites Houston – NASA Clear Lake

2.5 star property
8.2 out of 10, Very good, (806)
"Nice hotel just there is no space to unload luggage from car to trolley."
The price is ฿2,029
฿2,374 total
includes taxes & fees
14 Jan - 15 Jan
Sonesta Simply Suites Houston – NASA Clear Lake
SureStay Hotel by Best Western Deer Park
In-room safe, individually furnished, desk, laptop workspace

SureStay Hotel by Best Western Deer Park

2.5 star property
8.4 out of 10, Very good, (196)
" The room was nice as they gave me a first floor room per my request. Also. I was scheduled to come on a Thursday night for a Friday morning meeting. However, got word that my meeting was postponed to Monday at the last minute. I missed the deadline for cancellation/changes. So called to ask them to move reservation to Sunday night. They were kind to allow me to do this. "
The price is ฿2,161
฿2,528 total
includes taxes & fees
4 Jan - 5 Jan
SureStay Hotel by Best Western Deer Park
La Quinta Inn & Suites by Wyndham Houston/Clear Lake-NASA
Suite, 2 Queen Beds, Non Smoking | Premium bedding, desk, iron/ironing board, free cots/infant beds

La Quinta Inn & Suites by Wyndham Houston/Clear Lake-NASA

2.5 star property
7.8 out of 10, Good, (1004)
"Pros: Great beds; good shower; spacious rooms; nice staff Cons: both mornings they had NO knives for breakfast and told me they were out, but did not get more for the next day…. Very hard to cut sausage and waffles or spread butter without a knife! Additionally, no shower hooks in room for any towels; lobby and halls were at least 85 degrees and miserable at breakfast "
The price is ฿2,361
฿2,763 total
includes taxes & fees
26 Jan - 27 Jan
La Quinta Inn & Suites by Wyndham Houston/Clear Lake-NASA
Best Western Webster Hotel, Nasa
Seasonal outdoor pool, pool umbrellas, pool loungers

Best Western Webster Hotel, Nasa

2.5 star property
7.6 out of 10, Good, (1000)
"Best Western is a very nice and reasonable price place to stay."
The price is ฿2,287
฿2,676 total
includes taxes & fees
9 Jan - 10 Jan
Best Western Webster Hotel, Nasa
La Quinta Inn & Suites by Wyndham Houston Channelview
Exterior

La Quinta Inn & Suites by Wyndham Houston Channelview

3.5 star property
8.6 out of 10, Excellent, (662)
"We stayed for a weekend get away with the kids. This property did not disappoint. The front desk was accomdating when we needed towels and unexpectedly needed to change our stay to a leave day earlier. I wish i could have caught the gals name. But she was AMAZING! The parking lot is gated! The rooms clean and breakfast was very very good! Will stay again for sure. "
The price is ฿2,559
฿2,994 total
includes taxes & fees
19 Jan - 20 Jan
La Quinta Inn & Suites by Wyndham Houston Channelview
Holiday Inn Express & Suites Houston East - Beltway 8, an IHG Hotel
Exterior

Holiday Inn Express & Suites Houston East - Beltway 8, an IHG Hotel

2.5 star property
8.4 out of 10, Very good, (340)
"Everything was nice neat and clean. Staff was very friendly and helpful."
The price is ฿2,778
฿3,250 total
includes taxes & fees
5 Jan - 6 Jan
Holiday Inn Express & Suites Houston East - Beltway 8, an IHG Hotel
La Quinta Inn & Suites by Wyndham Pasadena
Room, 2 Queen Beds, Non Smoking | Premium bedding, individually furnished, desk, iron/ironing board

La Quinta Inn & Suites by Wyndham Pasadena

2.5 star property
7.8 out of 10, Good, (655)
"Property is going through major renovations. The first room we were assigned was very rough. The beds were flat with rust in the bathroom. I asked the front desk clerk and she was over the top amazing. She personally took me to another room to inspect. "
The price is ฿2,623
฿3,069 total
includes taxes & fees
27 Jan - 28 Jan
La Quinta Inn & Suites by Wyndham Pasadena
Palace Inn Blue Houston East Beltway 8
Reception

Palace Inn Blue Houston East Beltway 8

2.5 star property
9.0 out of 10, Wonderful, (232)
"Very good"
The price is ฿2,631
฿3,026 total
includes taxes & fees
19 Jan - 20 Jan
Palace Inn Blue Houston East Beltway 8
La Quinta Inn & Suites by Wyndham Pasadena North
Lobby

La Quinta Inn & Suites by Wyndham Pasadena North

2.5 star property
8.0 out of 10, Very good, (518)
"Front desk was friendly and helpful late check-in due to bad weather. The place is okay needs improvement the place smelled smokey and musty..Beware they charge 100 cash for incidental..I had no cash so waive for me...My negative was they hand you instructions on how yo use the shower..I thought it was a bit overprice for that Hotel..They serve breakfast and yes night shift prepares the food with a smokers cough..Better that most in the surroundings area.."
The price is ฿2,729
฿3,193 total
includes taxes & fees
3 Feb - 4 Feb
La Quinta Inn & Suites by Wyndham Pasadena North
Bluestar Inn
Individually furnished, desk, iron/ironing board, free WiFi

Bluestar Inn

2.5 star property
8.8 out of 10, Excellent, (189)
"Nice"
The price is ฿2,503
฿2,929 total
includes taxes & fees
5 Jan - 6 Jan
Bluestar Inn
Best Western Plus Heritage Inn
Reception

Best Western Plus Heritage Inn

3.0 star property
8.0 out of 10, Very good, (573)
"Overall experience was excellent!!"
The price is ฿2,685
฿3,142 total
includes taxes & fees
4 Jan - 5 Jan
Best Western Plus Heritage Inn
Woodspring Suites South Houston Hobby
Suite, 1 King Bed, Non Smoking | Individually furnished, desk, laptop workspace, bed sheets

Woodspring Suites South Houston Hobby

2.5 star property
7.8 out of 10, Good, (117)
"Awesome place!!!"
The price is ฿2,023
฿2,367 total
includes taxes & fees
4 Jan - 5 Jan
Woodspring Suites South Houston Hobby
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in South Main
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Frequently asked questions

What is South Main like?

You'll be sure to have fun exploring Houston's South Main neighbourhood. Consider a visit to NRG Park as part of your South Main travel plans.

Where is the best hotel for a stay in South Main?

Based on Expedia customer reviews, Comfort Suites near Texas Medical Center - NRG Stadium is the highest ranked property in South Main. This hotel is a short 9-minute walk from NRG Stadium, and it offers free breakfast and free parking. Other top choices in the neighbourhood include Candlewood Suites Houston Medical Center, an IHG Hotel and Wyndham Houston near NRG Park/Medical Center.

How many hotels should I expect to find in South Main?

If you're searching for places to stay in Houston, Expedia has something to meet your needs with 66 South Main hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in South Main, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best options available in South Main.

What can I see and do in this Houston neighbourhood?

NRG Park is an attraction you might want to check out while you're in South Main. While you're out sightseeing in Houston, make sure that you visit other sights such as NRG Stadium or NRG Arena.

How can I get around South Main and the greater Houston area?

Ready to get out and explore the city? Fannin South Station is the closest metro station.